Report on remission in patients with MS three years after stem cell transplant

Three years after a small number of patients with multiple sclerosis (MS) were treated with high-dose immunosuppressive therapy and then transplanted with their own hematopoietic stem cells, most of the patients sustained remission of active relapsing-remitting MS and had improvements in neurological function, according to a study. More...

Laparoscopic surgery for bladder cancer leads to good long-term cancer control

Long-term survival rates following laparoscopic surgery for bladder cancer are comparable to those of open surgery, according to a study. More...

How lungs protect themselves from infection

Scientists have taken an important step toward a new class of antibiotics aimed at stopping lung infections. More...

An inside job: Designer nanoparticles infiltrate, kill cancer cells from within

Nanoparticle designs target and treat early stage cancer cells by killing those cells with heat, delivered from inside the cell itself. More...

Major brain pathway rediscovered after century-old confusion, controversy

A scientist looking at MRI scans of human brains noticed a large fiber pathway that seemed to be part of the network that processes visual information. More...

Artificial retina could someday help restore vision

The loss of eyesight, often caused by retinal degeneration, is a life-altering health issue for many people, especially as they age. More...

First-in-class nasal spray demonstrates promise for migraine pain relief

Researchers are developing a novel prochlorperazine nasal spray formulation as a potential new treatment for migraines. More...

Labcorp will aquire Covance

LabCorp, the second largest clinical diagnostics company in the U.S., announced today that it will acquire Princeton, N.J.-based Covance (CVD) for $6.1 billion. More...

New nanodevice to improve cancer treatment monitoring

In less than a minute, a miniature device can measure a patient's blood for methotrexate, a commonly used but potentially toxic cancer drug. More...

Treatment for osteoporosis, bone cancer, employed for the first time in dental filling procedures

Researchers have demonstrated how the use of zoledronic acid, in combination with bioactive ion-releasing resin-based restorative materials used as dental adhesive, reduces the degradation of dentin collagen and promotes remineralisation at the resin-dentine interface. More...

New front in war on Alzheimer's, other protein-linked brain diseases

Proteins must fold into the right 3-D structure to work, and the body produces many chaperone molecules to refold misfolded proteins. More...

A glimpse into the 3-D brain: How memories form

People who wish to know how memory works are forced to take a glimpse into the brain. 
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Mimicking brain cells to boost computer memory power

Researchers have brought ultra-fast, nano-scale data storage within striking reach, using technology that mimics the human brain. More...

New 'designer proteins' in fight against Alzheimer's, cancer

Chemists at the University of Leicester have reported a breakthrough in techniques to develop new drugs in the fight against diseases such as cancer and Alzheimer's. More...

Imaging identifies asymptomatic people at risk for stroke

Imaging can be a cost-effective way to identify people at risk for stroke who might benefit from aggressive intervention, according to a new modeling study. More...

Antibiotics in early life may alter immunity long-term

A new study aims to help scientists understand how different antibiotics affect bacteria that play a positive role in promoting a healthy immune system. More...

Hospitals could face penalties for missing electronic health record deadline

Many of the nation's hospitals in the U.S. struggled to meet a federally mandated electronic health records deadline, and as a result could collectively face millions of dollars in reduced Medicare payments this year, a study shows. More...

New clues to repairing an injured spinal cord

Frogs, dogs, whales, snails can all do it, but humans and primates can't. More...

Surgical safety program greatly reduces surgical site infections for heart operations

A common postoperative complication after open heart operations -- infection at the surgical site More...

Older adults who walk out of necessity are at highest risk for outdoor falls

Older adults are at a greater danger of falling when walking for utilitarian purposes such as shopping and appointments than when walking for recreation, according to a study. More...

Study of noninvasive retinal imaging device presented at Alzheimer's conference

A noninvasive optical imaging device can provide early detection of changes that later occur in the brain and are a classic sign of Alzheimer's disease, according to preliminary results from investigators. More...

Viruses use 'fake' proteins to hide in our cell

Some viruses can hide in our bodies for decades and make 'fake' human proteins that trick our immune cells into believing nothing is wrong. More...

Unprecedented 3-D view of important brain receptor

Researchers have given science a new and unprecedented 3-D view of one of the most important receptors in the brain -- a receptor that allows us to learn and remember, and whose dysfunction is involved in a wide range of neurological diseases and conditions, including Alzheimer's, Parkinson's, schizophrenia and depression. More...

Researchers find portable, low-cost optical imaging tool useful in concussion evaluation

The findings from the optical-imaging research, employing functional near infrared spectroscopy (fNIRS), provided preliminary support for the tool as a low-cost, portable device for imaging sports and military concussions, researchers said. More...

Findings point toward one of first therapies for Lou Gehrig's disease

Researchers have determined that a copper compound known for decades may form the basis for a therapy for amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. In humans, prior to this, no therapy for ALS has ever been discovered that could extend lifespan more than a few additional months. More...

Statin use associated with less physical activity

Statins in older men is associated with less physical activity, a significant issue for a population that's already sedentary, concludes one of the longest studies of its type. More...

Anti-diabetic drug slows aging and lengthens lifespan, animal study suggests

Researchers have provided new evidence that metformin, the world’s most widely used anti-diabetic drug, slows aging and increases lifespan. More...

Sound and vision: Visual cortex processes auditory information, too

Sientists studying brain process involved in sight have found the visual cortex also uses information gleaned from the ears as well as the eyes when viewing the world. More...

Humans and companion animals harbor the same types of MRSA infections

Shared population of methicillin-resistant Staphylococcus aureus (MRSA) bacteria circulates both in humans and companion animals, according to a study published this week in mBio®, the online open-access journal of the American Society for Microbiology. More...

Patient stem cells used to make 'heart disease-on-a-chip'

Harvard scientists have merged stem cell and 'organ-on-a-chip' technologies to grow, for the first time, functioning human heart tissue carrying an inherited cardiovascular disease. More...

How does stress increase risk for stroke, heart attack?

Scientists have shown that anger, anxiety, and depression not only affect the functioning of the heart, but also increase the risk for heart disease. More...

Pfizer eyes AstraZeneca for $100 billion acquisition

After making a failed bid for AstraZeneca in January, pharmaceutical heavyweight Pfizer is again pursuing a deal for its British rival that would rank among the largest in industry history. More...

Finding turns neuroanatomy on its head

Harvard neuroscientists have made a discovery that turns 160 years of neuroanatomy on its head. More...

Sharpening microscope images: New technique takes cues from astronomy, ophthalmology

The complexity of biology can befuddle even the most sophisticated light microscopes. 

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Nature Genetics: LMP researchers offer hope for children with previously incurable brain cancer

Imagine the anguish of a parent whose child is diagnosed with an incurable form of childhood brain cancer. More...

Electric 'thinking cap' controls learning speed

Caffeine-fueled cram sessions are routine occurrences on any college campus. But what if there was a better, safer way to learn new or difficult material more quickly? What if "thinking caps" were real? More...

Hot nanoparticles for cancer treatments

Nanoparticles have a great deal of potential in medicine: for diagnostics, as a vehicle for active substances or a tool to kill off tumors using heat. More...

We must forget to avoid serious mental disorders, and forgetting is actively regulated

In order to function properly, the human brain requires the ability not only to store but also to forget. More...

New reason to eat oats for heart health

Eleven top scientists from around the globe presented the latest findings on the powerful compounds found in oats in a scientific session titled, Physicochemical Properties and Biological Functionality of Oats, at the 247th Annual Conference of the American Chemical Society in Dallas, TX. More...

Particle beam cancer therapy: The promise and challenges

Accelerator physicists are natural-born problem solvers, finding ever more powerful ways to generate and steer particle beams for research into the mysteries of physics, materials, and matter. More...

Unexpected findings: 'Promising' drug failed to improve survival in glioblastoma

"The results of this study are counter to most expectations," said Dr. Brachman, Director of Radiation Oncology at Barrow and St. Joseph's. "Bevacizuman had been shown in earlier studies to be an effective drug in the treatment of patients with recurrent disease. But, on newly diagnosed patients, it did not, in fact, prolong survival." More...

Antibody may be detectable in blood years before MS symptoms appear

An antibody found in the blood of people with multiple sclerosis (MS) may be present long before the onset of the disease and its symptoms, according to a study released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. More...

Can citrus ward off your risk of stroke?

Eating foods that contain vitamin C may reduce your risk of the most common type of hemorrhagic stroke, according to a study released today that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. More...

New imaging technique can diagnose common heart condition

A new imaging technique for measuring blood flow in the heart and vessels can diagnose a common congenital heart abnormality, bicuspid aortic valve, and may lead to better prediction of complications. More...

New heart valve deployed without major open surgery

An artificial heart valve device that does not require major open surgery has been approved by the Food and Drug Administration. More...

Investigators at Johns Hopkins report they have developed human induced-pluripotent stem cells (iPSCs) capable of repairing damaged retinal vascular tissue in mice. More...

Mechanism Identified in Alzheimer's-Related Memory Loss

Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted online today. More...

It's All Coming Back to Me Now: Researchers Find Caffeine Enhances Memory

For some, it's the tradition of steeping tealeaves to brew the perfect cup of tea. For others, it's the morning shuffle to a coffee maker for a hot jolt of java. More...

New Method for Efficiently Transporting Antibodies Across the Blood-Brain Barrier

Today the scientific journal Neuronpublished results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

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Disparities Run Deep: Parkinson's Patients Utilization of Deep Brain Stimulation Treatment Reduced in Demographic Groups

Among Parkinson's disease (PD) patients, female, black, and Asian patients are substantially less likely to receive proven deep brain stimulation (DBS) surgery to improve tremors and motor symptoms, according to a new report by a Perelman School of Medicine at the University of Pennsylvania researcher who identified considerable disparities among Medicare recipients receiving DBS for Parkinson's disease. More...